CATO CONSPIRACY The first serious slave uprising in the American colonies was the Cato Conspiracy of 1739. Led by a black slave named Cato, this uprising took place about twenty miles west of Charleston on a plantation at Stono. Hoping to reach Florida, Cato and about fifty to sixty slaves raided a warehouse, securing arms and ammunition. Marching to the beat of two drums, the conspirators began their trek south, killing any white who attempted to interfere. Pursued by a vigilante group of armed whites, the determined rebels, with the exception of about a dozen, were captured or killed. Before the conspiracy ended, a total of thirty whites and forty-four blacks lost their lives. See also: SLAVE CONSPIRACIES.